Can a drug make you tell the truth?
One of the great challenges of living in our society is knowing when people are telling the truth or not. We lie all the time and are remarkably bad at detecting when other people are deliberately deceiving us.
There are lots of urban myths about lie detecting, such as the claim that liars tend to look away, twitch their feet or touch their noses when lying (the so-called Pinocchio effect).
In study after study, it has been shown that professionals such as policemen are no more reliable at detecting liars than the rest of us. So it's not surprising that for many years scientists have been working to develop "truth drugs" - drugs that will make you open up and tell all you know to an interrogator.
One of the oldest and best known of these truth drugs is sodium thiopental. Although it was first developed in the 1930s, it is still used today in a range of settings, including, in some countries, by the police and the military.
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I was intrigued but also extremely sceptical about the claims that sodium thiopental, originally developed as an anaesthetic, could make people speak the truth if they chose not to. So I decided, as part of a series I've been making on the extraordinary history of pharmaceuticals, to try it out.
Sodium thiopental is part of a group of drugs called barbiturates, drugs widely used in the 1950s and 60s to help people sleep better. They are no longer used for that purpose because they are extremely addictive and potentially lethal - Marilyn Monroe famously died from a barbiturate overdose.
I decided to take a low dose of sodium thiopental under proper medical supervision, with anaesthetist Dr Austin Leach monitoring my vital signs throughout. Barbiturates work by slowing down the rate at which messages travel through the brain and spinal column. The more barbiturates there are, the harder it is for chemical messages to cross the gaps between one neuron and the next.
Your whole thinking process slows down until you fall asleep. With thiopental, that happens very quickly indeed.
Although it was originally developed as an anaesthetic, it was soon noticed that when patients were in that twilight zone halfway between consciousness and unconsciousness, they became more chatty and disinhibited. After the drug had worn off, the patients forgot what they had been talking about.
It was decided that sodium thiopental might form the basis for a truth drug, an interrogation tool. But does it really work?
I decided that I would have a go at trying to maintain the fiction that rather than being Michael Mosley, science journalist, I would be Michael Mosley, famous heart surgeon. We started with a very low dose. Immediately I felt extremely light-headed, intoxicated. But would this make me more inclined to speak the truth?
Sodium thiopental may work on our brains in the same way as alcohol
There is an expression, "in vino veritas" (in wine there is truth). Alcohol is an anaesthetic and it depresses some of our higher centres, areas like the cerebral cortex where a lot of thought processing occurs. It reduces inhibitions but also slows thought processes, making it difficult to think clearly. The Roman historian Tacitus claimed that Germanic tribes held their important councils while drunk, as they thought it made effective lying harder. LaNUBlog.comlatestarticlesbyiykemandela.blogspot.com
Do you think drug can make you tell the truth?
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